CIPHER grant program offering up to USD 150,000 over two years

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Deadline: 31-Oct-2022

The International Aids Society (IAS) is accepting applications for the Collaborative Initiative for Pediatric HIV Education and Research (CIPHER) grants program.

This program awards early career researchers up to US$150,000 over two years to fill gaps in pediatric and adolescent HIV research in countries with limited resources for HIV research. It is designed to provide researchers with the experience they need to compete for larger funding.

The purpose of the Collaborative Initiative for Pediatric HIV Education and Research (CIPHER) grants program is to fund research projects that have the potential to answer critical research questions that remain unanswered in the global response. . The ambition is to support research that can inform policy change and ensure better outcomes for infants, children and adolescents living with and affected by HIV in resource-limited settings.

Designed for beginning researchers. One of the main goals of the program is to build research capacity in resource-limited settings by nurturing the next generation of pediatric and adolescent HIV researchers. It is intended to attract young researchers from within and outside the field of HIV. This will help encourage innovative ideas and foster the design of evidence-based approaches and interventions to overcome key barriers on the ground.

Strategic axis 2022/2023 – Mental health
  • CIPHER has partnered with the World Health Organization to develop global research agendas on HIV testing, treatment and service delivery for pediatric and adolescent populations. CIPHER implements these research priorities through its research and fellowship programs. Eligible research projects include original research that may contribute to broader scientific endeavors by answering parts of broader questions within the identified research priorities, for example, sub-studies or the generation of important preliminary data that may help secure more substantial research funding for pediatric and adolescent HIV research. (See Appendix I). II.
Funding Information
  • Fellowships will be funded for up to two years and up to a total of 154,000% for two years (including direct research costs and applicable indirect costs). Funding for the second year is contingent on demonstrating satisfactory progress in the first year. The CIPHER grant program encourages collaborations between different study sites and institutions: at least 80% of direct grant expenses must be spent on twee.
Eligible Research Priorities
  • Eligible research projects include original research that addresses defined priority research questions. Meta-analyses and systematic reviews will also be considered if they provide unique contributions to the questions described.
  • Pediatric HIV (infants and children 0-10 years, including the perinatal and in utero period. studies of mother-infant pairs and uninfected children exposed to HIV)
    • Test
      • Optimal placement and timing of new diagnostic tools for point-of-care use;
      • Interventions to ensure a timely link between HIV diagnosis, treatment and care:
      • Interventions or strategies to improve access to and uptake of HIV testing services for infants and children, especially community-based approaches;
      • Factors that enable or hinder linkage to care and rapid initiation of ART;
      • Effective, feasible and acceptable testing strategies (including routine birth testing) at entry points other than the antenatal nucleus to identify undiagnosed HIV-positive infants and children in different epidemic settings.
    • Treatment
      • Safety, efficacy, acceptability. phormocokinetics and optimal dosing of existing and new antiretroviral drugs and formulations, especially with new drug delivery systems;
      • Strategies or interventions to improve adherence and factors that influence their success;
      • Optimal prevention and clinical management of co-infections, in particular tuberculosis;
      • Impact of HIV infection and ART on short-term and long-term outcomes, especially non-communicable diseases;
      • Short- and long-term virological and immunological outcomes of very early initiation of treatment in infants living with HIV (impact on functional cure).
    • Delivery service
      • Strategies or interventions to improve access, utilization and retention of care, and the factors that influence their success;
      • Service delivery models to improve individual and programmatic outcomes along the HIV cascade, including integrating comprehensive HIV treatment and care into the maternal and child health platform;
      • Psychosocial and family support strategies or interventions to improve individual and programmatic outcomes;
      • Strategies or interventions to improve and support parents, caregivers and health care providers to facilitate HIV disclosure to children, as well as factors that influence their success:
      • Strategies or interventions to reduce stigma and discrimination experienced by children and their caregivers.
  • Adolescent HIV (10 to 19 years old)
    • Test
      • Strategies and interventions to improve access to and uptake of HIV testing services, and factors influencing their success;
      • Strategies and interventions to improve the link between newly diagnosed adolescents and HIV treatment. and the factors that influence their success;
      • Safe and acceptable strategies or interventions to improve access to and uptake of HIV testing services for people from key populations;
      • Consent policies and practices to facilitate access to and uptake of HIV testing services among adolescents;
      • Safety, acceptability, feasibility and effectiveness of self-tests.
    • Treatment
      • Effective monitoring approaches and strategies to improve adherence among adolescents and the factors that influence their success;
      • Safety, efficacy and acceptability of navel drug delivery systems;
      • Prevention and clinical management of ca-infections. especially tuberculosis;
      • Optimal sequencing of ART in adolescents;
      • Impact of HIV infection and ART on adolescent short- and long-term outcomes, particularly non-communicable diseases.
    • Delivery service
      • Interventions to improve core retention and factors that affect their success;
      • Strategies or interventions to improve sexual and reproductive health Outcomes among adolescents living with HIV;
      • Strategies or interventions to support pregnant adolescents living with HIV and improve maternal and child health outcomes;
      • Service delivery models to improve outcomes along the HIV cascade, including peer-to-peer interventions and differentiated service delivery models; Strategies or interventions to support PSyChosociol to improve individual and programmatic outcomes.
Eligibility criteria
  • Anyone with the skills, formal education, and access to resources necessary to complete the proposed research is invited to apply for the CIPHER grants program. The applicant must be the Principal Investigator (PI) of the proposed project. The PI should work with a mentor, institutional colleagues and partners to develop the research plan.
  • Eligibility criteria and mandatory supporting documents:
    • The PI must be a junior researcher, i.e. someone who has completed their terminal research degree (e.g. PhD, MD, MOBS or equivalent) less than 10 years before the application deadline.
    • The PI must serve for the first time as a prknon, Pl. Primary pls who have previously received a non-training related research grant greater than 30,000 SEU are not eligible.
    • The IP must meet one of the following criteria by the LOI submission deadline:
    • He/she is a clinical trainee/researcher (e.g. fellow, senior resident) in a university institute or in an institute whose main mission is research.
    • He/she has a faculty or a comparable position (e.g. assistant professor, lecturer) of a university institute or an institute whose main mission is research.
    • He/she is in an established position in an organization with adequate research infrastructure to undertake the proposed research activities.
    • The research project must demonstrate the potential to contribute to the optimization of HIV diagnosis, treatment and care for HIV-affected infants and children in resource-limited settings by addressing identified research priorities.
    • Applications are encouraged from all countries, but please note that approximately 80% of funds available in any given year will be awarded to applicants from (i.e. passport holders from) income countries low and intermediate (PRFI) according to the World Bank classification. .
    • The PI should select a mentor with relevant expertise in pediatric HIV research (mentor contact details and letter of commitment will be requested from all applicants: a mentorship plan will only be requested from shortlisted applicants who are invited to submit a full proposal).
    • The budget should reflect that at least 80% of direct grant expenditures will be spent on the MICs.
    • A letter of support from the candidate’s institution is required, along with a copy of the candidate’s terminal research diploma.

For more information, visit https://www.iasociety.org/grants/cipher-grant-programme-2022-2023

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