Recent study finds cannabis helps treatment-resistant depression and alcohol dependence

Treatment-resistant depression is common. About 30% of people with depressive disorders have some form of depression that is resistant to treatments offered by traditional pharmaceuticals. This means that mood stabilizers and SSRIs don’t work to relieve their symptoms of depression.

A recent study of the Journal of Psychopharmacology called “Cannabis-induced oceanic infinityFound that high doses of cannabis can help improve symptoms of treatment-resistant depression and other mental disorders, including cancer-related distress, and even cigarette and alcohol addiction.

The study author states that THC, the compound in cannabis that produces the majority of its psychoactive effects, is “comparable to those identified in psilocybin trials that precede relief of cancer distress, treatment-resistant depression, alcohol problems and cigarette addiction. . “

The study found that high doses of cannabis resulted in 17-19% of people with treatment-resistant depression and distress reporting “breakthroughs” in improving their mental health. Psilocybin was still reported as offering Following Positive mental “breakthroughs” for people with treatment-resistant depression, 59% of respondents.

The study defines this breakthrough or feeling of “ocean infinity” as mystical experiences, which often result in a change in mental health. These mystical-type experiences are measured by “unity, spirituality, and insight on the 11-dimensional Altered States of Consciousness Questionnaire or comparable self-report scales,” say its authors.


SAGE ReviewsCannabis-Induced Oceanic Infinity – Mitch Earleywine, Luna F Ueno, Maha N Mian, Brianna R Altman, 2021

This study is not the only one examining notions about cannabis and mental health. Cannabis and its effects on mental health have had a sordid relationship in the scientific community over the past century, largely because cannabis has not been cleared for clinical research. Even today, cannabis has restrictions in place by the DEA so that only cannabis grown in their labs can be researched, and research cannot be done on cannabis sold in legal markets to consumers. United States. In May 2021, the DEA says it is “nearing the end of its reviewAnd anticipate changes in cannabis research.

Anxiety and depression are among the most common diseases in the United States with around 40 million people suffering from some form of mental problem. Experts say these the numbers were only made worse by the stress of the pandemic. Among adolescents, an estimated 3.2 million young people aged 12 to 17 in the United States suffer from depression and more than 17.3 million young adults over the age of 18 to 26. It is estimated that 30% of adults and 60.1% of adolescents who are depressed never get treatment.

In today’s regulations for every medical marijuana legal state, none of them mentions depression as an eligibility requirement for a medical card. Several states mention PTSD and anxiety as mental health conditions, but depression has long been left out of the conversation about the effectiveness of medical marijuana. One study that has garnered a lot of attention, but relies on less of a data pool than the other studies cited here, is as follows Study 2019 linking cannabis to higher rates of psychosis.

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This isn’t the only study that has been published on cannabis and mental health in recent years. A research paper “When they say the herb causes depression, but it’s your favorite antidepressant ”: conscious awareness framework of knowledge for extracting relationships.“This research team looks at self-reported data on Twitter and asks the question: Does cannabis cause depression or is it a potential treatment for depression? Do people heal themselves? He revealed that people use cannabis for depression, but the article is limited in that it does not differentiate between CBD and cannabis, so the effect of reducing anxiety and depression cannot be separately identified with CBD or THC cannabinoids. There are many studies that have found CBD reduces anxiety.

Additional research suggests that people who become adult medical marijuana patients may have self-treated with cannabis to reduce their own depression and anxiety before they are legally prescribed.

Pandemic stress and trauma have heightened Americans’ urgent need for mental health solutions. A study “Adult PTSD Symptoms and Substance Use During Wave 1 of the COVID-19 Pandemicc ”, found that the first wave of COVID-19 could be correlated with spikes in substance use. It found that 13.4% of women and 13.2% of men reported a significant increase in substance use as a result of the pandemic. The people most “stressed” among these people were adults between the ages of 18 and 35, people who feel they have contracted COVID, as well as people who have lost their jobs or income due to the illness. pandemic.


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